Prime Downtown San Mateo Commercial Space for Lease Ideally located at 706 N San Mateo Drive, this charming and versatile commercial space offers ~1,382 sq ft in the heart of vibrant Downtown San Mateo. Situated along a high-visibility corridor with strong foot and vehicle traffic, this property provides excellent exposure for a wide range of business uses. The space offers multiple rooms that can accommodate private offices, consultation rooms, creative studios, or flexible work areas. A kitchen and bathroom along with laundry facilities are included, and the layout allows for efficient operations and client-facing use. Individual rooms also available for lease. Just steps from popular shops, restaurants, public transportation, and major commuter routes, this location is ideal for professional services, boutique retail, wellness practices, or creative businesses seeking a central Peninsula presence. Dont miss this opportunity to establish your business in one of San Mateos most desirable and walkable commercial districts.