Prime ground-floor commercial space available along the highly trafficked Mission Street corridor. This well-positioned storefront offers excellent visibility, strong pedestrian activity, and convenient access to public transportation. The space features a wide frontage, large display windows, and an efficient open layout suitable for a variety of neighborhood-serving retail or service uses. Located in a dense residential and commercial area, the property benefits from consistent foot traffic and nearby amenities. Ideal for retail, personal services, professional offices, or other permitted commercial uses. Excellent opportunity to establish a presence in one of San Franciscos most active corridors. Highlights: Prominent Mission Street frontage Strong foot and vehicle traffic Ground-floor storefront Flexible open layout Close proximity to BART, MUNI, and bus lines Surrounded by dense residential and commercial uses
Property Details
Price:
$1,999
MLS #:
ML82029485
Status:
Active
Beds:
0
Baths:
0
Type:
Single Family
Subtype:
Commercial/Residential
Listed Date:
Dec 15, 2025
Lot Size:
10,084 sqft / 0.23 acres (approx)
Year Built:
1977
See this Listing
Schools
Interior
Exterior
Roof
OTH
Financial
Map
Community
- Address4221 Mission ST San Francisco CA
- CitySan Francisco
- CountySan Francisco
- Zip Code94112
Subdivisions in San Francisco
Market Summary
Current real estate data for Single Family in San Francisco as of Mar 09, 2026
93
Single Family Listed
87
Avg DOM
627
Avg $ / SqFt
$1,262,463
Avg List Price
Property Summary
- 4221 Mission ST San Francisco CA is a Single Family for sale in San Francisco, CA, 94112. It is listed for $1,999 and features 0 beds, 0 baths, and has approximately 0 square feet of living space, and was originally constructed in 1977. The average price per square foot for Single Family listings in San Francisco is $627. The average listing price for Single Family in San Francisco is $1,262,463.
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